ENRO-COL ORAL is a combined veterinary oral solution containing enrofloxacin and colistin. According to the manufacturer, each milliliter provides 100 mg enrofloxacin and 1,200,000 IU colistin sulphate. The formulation brings together two antibacterial agents with different mechanisms and distribution profiles. Enrofloxacin is a fluoroquinolone antibiotic with bactericidal activity through inhibition of bacterial DNA replication enzymes, while colistin is a polymyxin antibiotic that disrupts the outer membrane of susceptible Gram-negative bacteria.
\nEnrofloxacin has activity against a range of clinically important veterinary organisms including E. coli, Salmonella, Pasteurella, Staphylococcus, Streptococcus, Klebsiella, Campylobacter and selected Mycoplasma species. Colistin, by contrast, is poorly absorbed after oral administration and therefore remains active mainly within the intestinal tract. The combination is intended to provide both systemic and intestinal antibacterial coverage when infections are caused by organisms that are susceptible to the active ingredients.
\nProduct information lists gastrointestinal and respiratory infections among the main indications and includes conditions associated with Mycoplasma, infectious coryza organisms, Pasteurella, E. coli, urinary-tract infections, wound infections and secondary bacterial complications of some viral diseases. ENRO-COL ORAL is administered through drinking water and should be shaken well before use. Accurate preparation, monitoring of water intake and use of freshly prepared medicated water are important to ensure appropriate treatment exposure.
\nThe product requires particularly responsible antimicrobial stewardship because it contains both a fluoroquinolone and colistin, antimicrobial classes for which resistance management is a major animal- and public-health priority. Use should be limited to clinically justified cases, and bacterial culture and susceptibility testing should be performed whenever feasible. Routine or unnecessary prophylactic use should be avoided. Animals with known hypersensitivity to enrofloxacin or colistin, or with severe renal or hepatic impairment, may not be suitable candidates, and restrictions for laying birds producing eggs for human consumption must be followed according to the local authorization.
\nENRO-COL ORAL is for veterinary use only. This product description is intended as a clear website overview and does not replace the official package leaflet, the approved local prescribing information or professional veterinary advice. Always comply with the stated dosage, treatment duration, withdrawal period, contraindications, storage conditions and handling precautions.<\/p>\n","protected":false},"featured_media":9477,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[96],"product_tag":[],"class_list":["post-9474","product","type-product","status-publish","has-post-thumbnail","product_cat-vetko","first","instock","shipping-taxable","product-type-simple"],"yoast_head":"\n